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Immune Mechanisms of Hypertension

Immune Mechanisms of Hypertension

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  • Michael J Ryan
  • Morgan & Claypool
  • Paperback
  • 9781615045822
  • 9.25 X 7.5 X 0.17 inches
  • 0.35 pounds
  • Science > Life Sciences - Human Anatomy & Physiology
  • English
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Book Description

In the vast majority of patients, hypertension has no identifiable cause. Moreover, despite decades of discovery and therapeutic development, approximately only half of the hypertensive patients are achieving clinically recommended blood pressure control. For these reasons, there has been continued interest in studying the factors that underlie the pathogenesis of hypertension. One area of research that has garnered significant attention is the potential link between immune system activation and blood pressure. Several lines of evidence, dating back several decades, support the concept for this association. This monograph gives a history of the early studies linking immune system function with hypertension and an overview of the large number of studies published in the past decade. The major focus is on the components of the innate and adaptive immune systems for which there is considerable evidence of their contributions to blood pressure control. Table of Contents: Introduction / The Immune System: Key Players / Immune System Activation and Human Hypertension / Long-Term Blood Pressure Control: Role of the Kidneys / Early Animal Experiments on Immune Function and Hypertension in Animals / Cytokines and Inflammatory Mediators in Experimental Hypertension / Innate Immune Contributions to Hypertension / Adaptive Immune Contributions to Hypertension: Role of T Cells / Adaptive Immune Contributions to Hypertension: Autoimmunity / Mechanisms and Perspectives / References / Author Biography
Immune Mechanisms of Hypertension

Author Bio

Michael J. Ryan is the Clark Hubbs Regents Professor in Zoology at the University of Texas, Austin. He received a BA in Life Sciences at Glassboro State College in New Jersey (1975), an MS in Zoology from Rutgers University at Newark (1977), and his Ph.D. in
Neurobiology & Behavior from Cornell University (1982). 

He was then a Miller Postdoctoral Fellow in the Museum of Vertebrate Zoology at the University of California at Berkeley (1982-1984) before beginning a position as an Assistant Professor at the University of Texas where he has remained. He has been a Research Associate at the Smithsonian Tropical Research Institute in Panama since 1982, and currently is a Senior Research Associate there. Ryan’s primary research interests are in the evolution and mechanisms of animal behavior, especially animal communication and sexual selection.

Ryan is a Fellow of the American Academy of Arts & Sciences, the American Association for the Advancement of Science, the Guggenheim Foundation, and the Institute for Advanced Studies in Berlin. He has received the Distinguished Animal Behaviorist Lifetime Achievement Award from the Animal Behavior Society (2017), the E.O. Wilson Naturalist Award from the American
Society of Naturalists (2010), the Joseph Grinnell Medal from the Museum of Vertebrate Zoology (UC, Berkeley; 2008), and the Exemplar Award from the Center for Integrative Studies in Animal Behavior (Indiana University, 2007). 

He also was selected as one of the 25 Leaders in Animal Behavior (book published 2010, Cambridge Univ. Press). Ryan has presented more than 150 invited lectures. He has also published more than 350 scientific papers (excluding Perspectives, News & Views, Primers, etc.) including 13 scientific papers in Science, 3 in Nature, 5 in PNAS USA, and 4 in Current Biology. He has also published five books, two as sole author, one co-authored, and two edited volumes. His 1985 book The Túngara Frog, A Study in Sexual Selection and Communication is considered a classic in its field, and most recently in 2018, A Taste for the Beautiful, The Evolution of Attraction.

Ryan has served on numerous external reviews for science departments, has been a panel member for the National Science Foundation, and served on numerous editorial boards. 

He is currently on the Board of Reviewing Editors for Science which he first joined in 2011, and is chairman of the Scientific Advisory Board of the Max Planck Institute in Seeweisen, Germany, he has been on that board since 2010

 

 

Source: The University of Texas - College of Natural Sciences

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